SCAI's ebook on Mechanical Circulatory Support (MCS) provides an in-depth, structured approach to understanding cardiogenic shock and the use of MCS devices. Organized into five sections, the Ebook covers essential topics from introductory concepts to device selection and future trends in the field. Whether you're a clinician, educator, or researcher, this comprehensive Ebook will enhance your knowledge of critical MCS technologies and their application in improving patient care.

Section 1: Introduction to Cardiogenic Shock and Therapies

• Chapter 1: Cardiogenic Shock Overview
• Chapter 2: Cardiogenic Shock in Heart Failure versus Acute Myocardial Infarction: Unraveling the Differences Between the Phenotypes
• Chapter 3: Understanding Intracardiac Hemodynamics: A Refresher on Interpreting PV Loops
• Chapter 4: Cardiogenic Shock Terminology and Metrics Explained
• Chapter 5: Hemodynamic Assessment: Right Heart Catheterization
• Chapter 6: Pharmacotherapy Overview: Inotropes, Vasopressors, and Vasodilators
• Chapter 7: Treatment Escalation Guidelines
• Chapter 8: Systems of Care: Shock Protocols, Teams, Centers, and Networks

Section 2: Basics of Mechanical Circulatory Support

• Chapter 9: Patient Identification and Device Selection
• Chapter 10: Access and Closure Techniques in MCS
  • 10.1: Best Practice Algorithm for Large Bore Femoral Artery Access
  • 10.2: Large Bore Femoral Venous Access and Closure
  • 10.3: Suture-based Closure Devices for Large Bore Access
  • 10.4: Closure Devices: Plugs, Patches, Hybrid
  • 10.5: Manual Compression and Assisted Manual Compression for Large Bore Access and Closure
  • 10.6: Cross-over Balloon Occlusion "Dry Closure" Technique for Large Bore Femoral Access
  • 10.7: Large Bore Arterial Post-Closure Hemostasis
  • 10.8: Access Strategies for Monitoring or Prolonged MCS Use
  • 10.9: Delayed Closure Techniques
  • 10.10: Percutaneous Axillary Artery Access Best Practices
  • 10.11: Distal Limb Perfusion Strategies
• Chapter 11: Anticoagulation Strategies and Patient Considerations When Using MCS
• Chapter 12: Vasoinotropic Considerations with Short-Term MCS

Section 3: In-Depth Review of Devices

• Chapter 13: Pulsatile Devices
  • 13.1: IABP and iVAC2L Mechanism of Action & Clinical Data
  • 13.2: Pulsatile Devices: Troubleshooting Complications
  • 13.3: Axillary-Subclavian Intra-aortic Balloon Pump Insertion
• Chapter 14: Impella® Family of MCS Axial Flow Pumps
  • 14.1: Impella® Mechanism of Action
  • 14.2: Troubleshooting Complications for Impella Left-sided Devices
  • 14.3: Impella RP® Insertion, Tips & Tricks, and Challenges
  • 14.4: Transcaval Access for Mechanical Circulatory Support
  • 14.5: Single Access Technique for Impella Assisted High-risk PCI
  • 14.6: Initial Management of the Impella® in the ICU
• Chapter 15: TandemHeart® Device
  • 15.1: TandemHeart: Clinical Data and Mechanism of Action
  • 15.2: Transseptal Access
  • 15.3: Troubleshooting TandemHeart® Complications
• Chapter 16: ECMO Overview
  • 16.1: ECMO Program Development
  • 16.2: ECMO Approved Devices
  • 16.3: VA vs VV ECMO: Why, When and How?
• Chapter 17: VA ECMO
  • 17.1: Introduction to VA ECMO
  • 17.2: Common Access Strategies for VA ECMO
  • 17.3: LAVA ECMO
  • 17.4: Common VA ECMO Management Issues
• Chapter 18: VV ECMO
  • 18.1: Introduction to VV ECMO
  • 18.2: Common Access Strategies: 2-site vs 1-site Peripheral Access
  • 18.3: ECMO Daily Management
• Chapter 19: ECMO Patient Management, Weaning, Troubleshooting, LV Unloading, and Closure
  • 19.1: Managing VA ECMO in the ICU
  • 19.2: Anticoagulation & Transfusion Strategies in ECMO
  • 19.3: ECMO Complications
  • 19.4: Unloading the LV When Using ECMO
  • 19.5: Weaning and Decannulation of VV and VA ECMO
  • 19.6: ECMO Access Site Closure: OR, Cath Lab, Bedside

Section 4: Selecting Devices and Device Combinations Based on Clinical Need

• Chapter 20: AMICS/Post PCI Shock
• Chapter 21: Isolated RV Support: Impella RP® and TandemHeart®
• Chapter 22: Biventricular Support Without ECMO
• Chapter 23: Weaning of Mechanical Circulatory Support
• Chapter 24: MCS Considerations in Acute Myocarditis, Chronic Decompensated HF, and AMI Cardiogenic Shock

Section 5: Future Innovations

• Chapter 25: Mechanical Circulatory Support Innovations and Future Directions

All Authors: Ahmad A. Abdul-Aziz, MD; Khaldoon Alaswad, MD, FSCAI; Hussayn J. Alrayes, DO; Manoj Ambalavanan, MD; Amer K. Ardati, MD, MSc, FSCAI; Cristina Aurigemma, MD, PhD; Avijit Bagga; Mir Babar Basir, DO, FSCAI; Wayne B. Batchelor, MD, FSCAI; Alessandro Beneduce, MD; John E. A. Blair, MD; John Blair, MD; Michael I. Brener, MD; Paul Brocklebank, BS; Kent Brummel, MD; Daniel Burkhoff, MD, PhD; Francesco Burzotta, MD, PhD; Alaide Chieffo, MD; Haval Chweich, MD; Mauricio G. Cohen, MD, FSCAI; Tawseef Dar, MD; Kathryn Dawson, MD; Mehul Desai, MD; Helena Dickens, BS; Allison G. Dupont, MD, FSCAI; Stephanie Dwyer Kaluzna, PharmD, BCCP; Marvin Eng, MD, FSCAI; Matthew C. Evans, MD; Anthony J. Faugno, MD; Christopher M. Fernandez, MD, MHS; Vamshidhara Gade, MD, FSCAI; Theresa Ganoe, ACNP-BC; A. Reshad Garan, MD, MS; Nadim A. Geloo, MD, FSCAI; Ahmed Ghoneem, MD, MSc; Waqas Ghumman, MD; Eric M. Gnall, DO; Kari Gorder, MD; Jason J. Grady, NRP; Mario Gramegna, MD; Hiram G. Bezerra, MD, PhD; Adam B. Greenbaum, MD; Jagpreet Grewal, MD; Elliott M. Groves, MD, MEng; Jaime Hernandez-Montfort, MD, MPH, MSc; Khalil Ibrahim, MD; Akinobu Itoh, MD, PhD; Ginger Jiang, MD, MBA; Viktoriya Kagan, APN-BC; Amir Kaki, MD, FSCAI; Navin K. Kapur, MD, FSCAI; Kameel Kassab, MD, FSCAI; Manu Kaushik, MD; Kathleen Kearney, MD, FSCAI; Maxwell Kilcoyne, DO; Arman Kilic, MD; Christopher A. King, MD, FSCAI; Nathan W. Kong, MD; Leah B. Kosyakovsky, MD; Ankit Kumar, MBBS; Anshita Kumari, MBBS; Katherine Kunkel, MD, MSEd, FSCAI; Emily Larnard, MD; James Lantry III, MD; John M. Lasala, MD, PhD, FSCAI; Kusum Lata, MD, FSCAI; Robert J. Lederman, MD, FSCAI; Ran Lee, MD; Alejandro Lemor, MD, MS, FSCAI; Michael J. Lim, MD, FSCAI; Jaya Mallidi, MD, MHS; Ashvarya Mangla, MD, FSCAI; Anbukarasi Maran, MD; Jeffrey A. Marbach, MBBS, MS, FSCAI; Miguel Martillo, MD; Nick Martini, CCP; James M. McCabe, MD, FSCAI; Jonathan Meyer, MD; Sandeep Nathan, MD, MSc, FSCAI; Charlie Nix, RN; Araba Ofosu-Somuah, MD; William W. O’Neill, MD, MSCAI; Brian O’Neill, MD; Erik A. Osborn, MD; Ki Park, MD, MS, FSCAI; Chirdeep Patel, MD FSCAI; Luis H. Paz Rios, MD, FSCAI; Ashish Pershad, MD, FSCAI; Duane S. Pinto, MD, MPH, FSCAI; Marie-France Poulin, MD, FSCAI; Alastair Proudfoot, MBChB, PhD; Donald Quimby Jr. MD; Morgan H. Randall, MD, FSCAI; Bharath G. Rathakrishnan, MD, FSCAI; Mark J. Ricciardi, MD, FSCAI; Toby Rogers, MD, PhD; Carolyn S. Rosner, NP; Siddharth Sarangi, MD; Anna Mara Scandroglio, MD; Theodore L. Schreiber, MD, FSCAI; Anish Shah, MD, MS; Madhan Shanmugasundaram, MD, FSCAI; Adhir R. Shroff, MD, MPH, FSCAI; Ramesh Singh, MD; Shashank S. Sinha, MD; Timothy D. Smith, MD, FSCAI; Joaquim Spadoni Barboza, MD, FSCAI; Michael Sumner, DO; Pooja Swamy, MD; Ranya Sweis, MD, MS, FSCAI; Rajiv Tayal MD, MPH; Behnam N. Tehrani, MD; Duc Thinh Pham, MD, FACS; Thomas M. Todoran, MD, MSC; Carlo Trani, MD; Ilan Vavilin, MD; Robert J. Widmer, MD PhD; Philipp Wiesner, MD; Jason Wollmuth, MD, FSCAI; Neha Yadav, MD; Jeffrey P. Yourshaw, MD, FSCAI; Rami Zein, DO; and Katrine A. Zhiroff, MD, FSCAI.