Many people with diabetes develop at least mild cardiovascular disease. Therefore, treatment consists of a strong program for preventing further damage to the heart and blood vessels, coupled with specific therapies for problems that already exist. Whether plaque build-up affects the arteries of the heart, legs, brain or other organs, effective prevention and treatment are likely to involve lifestyle changes, such as diet, exercise, stress management and quitting smoking; medications to control blood sugar, blood pressure and cholesterol levels; and possibly daily aspirin to ward off unwanted blood clots.