Kimberly Skelding, M.D., FSCAI, has never been one to shy away from a challenge. Perhaps that’s why, at just 36 years old, she is one of the principal investigators on the CardioGene study, a research project supported by the National Heart, Lung, and Blood Institute that is examining the role of patients’ genes when plaque forms inside an artery previously opened by a stent, a process known as in-stent restenosis. In other words, why is plaque more likely to build up in the arteries of some patients, while not in others?