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  • Unit 9.4: Drug-Eluting Stent Systems With Limited Success

    Alexandre Abizaid, MD, PhD — Instituto Dante Pazzanese de Cardiologia and Columbia University Medical Center, Cardiovascular Research Foundation

    Duration:1 hour


    Faculty Disclosure

    Disclosures not available


    Learning Objectives

    • Summarize the clinical trials using non-polymer paclitaxel-eluting stents, and explain the difference between these trials and the trials using polymer-based paclitaxel-eluting stents
    • Describe the mechanism of action of actinomycin D, tacrolimus, MPA, and batimastat, and explain the difference between these actions and the mechanism of action of sirolimus/paclitaxel
    • Discuss the possible reasons for less effective DES in clinical trials